The guy in Otoy forums sais: "Air cooled, turn the fan up at 75% and the max temperature is 70C for continuous Octane rendering. It could be lower if you crank the fan up. "
“The highest temperature are the first two cards, the last two are in 50-60 something.”
As I noticed, he runs his gpus slightly oc’ed too. So, imo, if you leave your gpus at stock speeds, you should have very decent temps while rendering.
The build you posted is like the one I suggested, with the exception of the chassis and RAM. If you want this Thermaltake, go for it. As long as it fits your needs and aesthetics, it’s fine. If you chose it because of it’s liquid cooling capabilities, then you already have the answer. No need for hybrid gpus. The FE 1080Ti’s would run cool enough, even if you install 4 of them stacked upon each other. So, my opinion is that you should get a chassis smaller in size, but airy enough to cool your system.
Why do you want the G.Skill RAM? This kit is more expensive and runs at lower speeds than the one I’ve posted before. Any reason for this particular choice?
Why a 250gb ssd? With your budget a 500gb should be a minimum imo.
As for your previous questions, yes, you can overclock each core at different speeds, but let me start by saying that you shouldn’t be so afraid of oc. I have my cpu (5960X) at 4.2GHz and with the “Per Core” frequency feature of the BIOS, I run the first 2 cores at 4.4GHz for better single core performance. The Vcore (which is the main Voltage you should care about when oc) is set to 1.22V and everything runs smoothly for 24/7. As long as you feed your cpu with the correct voltages and keep it at low temps, it will be stable for a long time.