I don’t really understand what you mean with less wires. You can use a wireless mouse and a wireless keyboard. But a monitor and the pc still needs to be plugged in somewhere and to be connected with each other. Good monitors have slots at the back where you can hide the wire to some degree. But they are not wireless.
For the ram and since you don’t want to upgrade at a later point. I would go with 32 gb. You want to work with video material. This can quickly sum up.
Apple is no good machine for graphics anymore. I would go with Windows nowadays.
Still no word at the budget, so i can just guess.
For the processor, AMD is in front at the moment. So pick a pc with an actual model. Like an AMD 3700x or 3950x. For the graphics card. The problem with making graphics is that most graphics software still relies at Cuda. That’s a special piece of driver software to speed up things, and just available for Nvidia graphics cards. The AMD part, OpenGL or Vulkan, does not work everywhere. So i would have a look to pick a Nvidia graphics card.
If that was too technical for you, which i fear, then as told, pick an actual gamer pc with 32 gb ram, an AMD processor, a Nvidia graphics card and a Windows 10 Pro license. This should do the job.
And cleaning and maintenance is the way it is. Dust bunnies are the enemy of electronic hardware. You have to remove them from time to time 
Kind regards - Tiles