I’m not sure what it is (since some days it works other it doesn’t) but there are times that 2.5 sucks down my CPU.
2.36-2.49 have always run smoothly on my comp and I could have 3mil+ polys before it slows down or crashes , my current project is just 500K+/- and it rotates slowly and can some times take 30-40 secs to switch from edit to object mode. I do have a subsurf on my model and when I change the number viewed it can take 2-5 minutes, 2.49 is near instant still. But as I said earlier some days 2.5 works just fine (though I have never been able to go above lvl 2 subsurf with out a crash though I can go to lvl 4 on the same model in 2.49)
I’ve also notice that renders take longer as well