s screens? you mean more than 1 monitor? i use 2 hd monitors myself. i use mouse mode on everything but! i set my wacom settings to be pen mode strictly on mudbox AND i map it this way:
monitor mapping: the 1 main screen +20% of the other screen from the center(so i can have menus in mudbox placed on my other monitor and not lose my pen range). and the tablet mapping is “roughly” the same ratio as the monitors space i mapped. meaning i dont use the whole tablet’s space to be mapped but more of a rectangle shape. this way you can kinda~ get a correct aspect ratio of your mapping so the square tablet wont be mapped to x2 the horizontal screen space…and drawing a circle results in a long ellipse, atleast not as much.
i know it sucks, i hate it… i hate pen mode. but this is the only way as far as i know, can send a hate mail to autodesk demanding they support mouse mode.
you can not use mouse mode period, stamp spacing will not work at all with mouse mode. and without stamp spacing you will get jaggy strokes with your tablet, useless to sculpt. not to mention your falloff/brush gets cut off in depth and as i said intensities dont work right, no pressure. making mudbox completly useless… just like a macintosh (heh).
no other solution, if you find something though let me know!