Hey. lot’s of different setups between us for sure, and many the same, such as “t” = tweak 
My setup is totaly different in many respects than most of yours, and though maybe not be as good as some, I quickly got used to it and feel right at home using such:
F1 = move normal
F2 = move x
F3 = move y
F4 = move z
F5 = extrude region normal ( I use this as extrude most of the time unless I specificaly require the seperations extrude delivers )
alt/F5 = extrude normal
F6 = extrude x
F7 = extrude y
F8 = extrude z
F9 = scale uniform
F10 = scale x
F11 = scale Y
F12 = scale z
- = rotate x
= = rotate y
\ = rotate z
h= bump
I = inset
Shift/b = bevel
alt/I = similar
m = VM create
n = VM freeze
alt/n = VM break
k = loop cut
; = previous loop
’ = next loop
, = select less
. = select more
j = bridge
p = put on
u = undo
The rest are basicaly default
Now I know that the F keys are way up there, and feel kinda awkward at first, but once ya get used to them it’s almost too easy just sliding side to side by feel, also, I find that placing the keyboard down on your lap allows for the angle to become comfy when working with these keys like this, especialy when your chair has armrests to rest your arms on.