Matthew:
You have a four-year degree and thus know how to study and learn hopefully. Check out some Gnomon Workshop DVDs (in area that you want to focus) as well as eat3D, 3D Motive, etc. There are workshops here on CG Society as well as other sites. Gnomon is a good school, but you can post work and get feedback here and other sites as well as take a workshop and get critiques. There are at least six video game/CG developers (and even an animation studio in West Burlington that relocated from California) in Iowa (and a couple in Omaha, NE). The Indie scene is growing in the Midwest (much lower cost of living, less congestion, and other reasons). I’m aware of a couple of Midwest business incubator programs for CG/VFX related growth that will hopefully help build some smaller and Indie firms. If you like the Midwest there are possibilities (and a $150,000 house in Iowa with lots of land would skyrocket to $750,000 to over $1,000,000 in California and the taxes and cost of living there are outrageous. You need entertainment/social life? You can fly once a month or more to other areas and still save a ton of money (and escape the crowd when you leave)). Check out the cost of living in LA before you decide on Gnomon also.
Good luck
